HLA-DRB1 and systemic lupus erythematosus: While not reaching the genome-wide significance threshold, there had been a suggestive association of HLA-DRB1*08:03 with primary biliary cholangitis in the Japanese population (OR, 1.75, P = 1.0 × 10−7)29, and one with systemic lupus erythematosus (SLE) in the Korean population (OR, 1.59, P = 7.4 × 10−8)30.