The results showed higher expression of TP73-AS1 in glioma samples of WHO grade IV than in glioma samples of WHO grade IV (p=0.002) (Figure 7A), and high TP73-AS1 expression predicted a poorer prognosis than low TP73-AS1 expression (P=0.048) (Figure 7B); these findings agreed with our preliminary results. This evidence concerns the gene TP73 and central nervous system cancer.