TP53 and cancer: Interestingly, by focusing on the well-known cancer genes, we discovered that some of our human iPSC-derived TNNT2+ cardiomyocytes were MYC+ and TP53-, including that although proto-oncogene activation and TSG defection are not commonly found in the majority of cells, they may be present in some human iPSC-derived cardiomyocytes.