FGF4 and neoplasm: Further gene molecular network (Fig. 4D) and gene ontology enrichment analysis (Fig. 4E) revealed that these 24 genes were enriched in growth factor-related pathways, For example, FGF4, BMP4, DKK1 and TDGF1 present in our study were also identified as promoters of tumor growth (Katoh, 2007; Selga i Coma et al., 2009).