In order to confirm these findings in a different genetic background and to avoid the limitation of using a single cell line, we knocked out LAMC2, MFGE8, KLK5, KLK7, and SLC2A1 genes in another TNBC cell line (SUM159PT, hereafter referred to as SUM159, derived from a patient with anaplastic breast carcinoma). The gene discussed is LAMC2; the disease is pleomorphic breast carcinoma.