NSD2 and head and neck squamous cell carcinoma: Given that all three NSD paralogs are expressed on average at significantly higher levels in HPV+ HNSCC, but only NSD2 had a statistically significant positive Spearman correlation coefficient with the HPV oncogenes, we next wanted to determine if individual tumors expressed high levels of a single NSD paralog on a mutually exclusive basis, or if their expression might be coordinately regulated.