In cervical cancer cell line, curcumin inhibited proliferation, invasion, stemness of cervical cancer cells through impairing Wnt/β-catenin and NF-Kβ pathways [127] The combination of conventional chemotherapy with Wnt/β-catenin inhibition can improve therapeutic effect by eliminating aggressive osteosarcoma CSCs and reducing therapy resistance [128]. This evidence concerns the gene NFKB1 and cervical carcinoma.