CXCL2 and nonpapillary renal cell carcinoma: Zhang et al. (40) reported that A-kinase-interacting protein 1 is crucial in CC angiogenesis and growth because it functions to elevate the levels of the NF-κB-dependent chemokines CXCL1, CXCL2, and CXCL8. Zheng et al. (41) revealed that chemokine CXCL2 induced lung cancer-associated transcript 1 (LUCAT1) overexpression and that the CXCL2β axis is a potential therapeutic target and molecular biomarker for clear cell renal cell carcinoma (ccRCC).