CYP2C8 and infection: There was no significant difference in the proportion of subjects carrying either CYP2C8*2 or CYP2C8*3 alleles amongst those with re-infections (44.1 %; 95 % CI 33.8–54.8) or those with recrudescent infections (48.3 %; 95 % CI 29.4–67.5), compared to those with ACPR (36.7 %; 95 % CI 30.0-43.9) (P = 0.25 and P = 0.31, respectively).