In line with our findings, the results by Mo PZ et al. [17] showed that 85 refractory patients had higher levels of maximum temperature among fever cases, higher incidence of breath shortness and anorexia, severer disease assessment on admission, high levels of neutrophils, aspartate aminotransferase (AST), LDH and CRP, lower levels of platelets and albumin, and higher incidences of bilateral pneumonia and PE (45.2%). The gene discussed is ALB; the disease is Anorexia.