In addition, studies reporteddisease-specific measures such as pain, C-reactive protein, Healthassessment questionnaire (HAQ) scores, Joint dysfunction and ErythrocyteSedimentation Rate (ESR) in RA; blood glucose levels (HbA1c) in T1D andT2D; disability scores in MS and Viral load and CD4 count in HIV.Physical outcomes were reported in seven studies, five of whichdemonstrated a statistically significant improvement in at least onephysical outcome. This evidence concerns the gene CD4 and rheumatoid arthritis.