INS and Insulin resistance: The results obtained in the mRNA expression of LPL, a major enzyme directly correlated with insulin resistance [46], PPARα, a pro-ketogenic protein involved in insulin-stimulated glucose uptake and fatty acid catabolism [47, 48], and PPARγ, a white adipose tissue marker involved in adipogenic mechanisms and storage of lipids in the liver [49], are also an indication of the 1144-induced improvement.