MKI67 and brain neoplasm: An evaluation of the gene expression of proteins implicated in proliferation, apoptosis, and response to OS in male brain tumors depicted that the inhibition of the systemic effects (loss of body weight and liver mass, plus reduced liver mitochondria mass) was linked to an increase in Bcl-2 and catalase and a decrease in Ki-67, SOD-1, and SOD-2 (Pouliquen et al., 2008).