MCAM and melanoma: For detecting CTCs, some of the previous melanoma CTCs markers used include melanoma-associated chondroitin sulfate proteoglycan (Ulmer et al., 2008; Suesskind et al., 2011; Eide et al., 2015), melanoma cell adhesion molecule (CD146), NKI/beteb and NKI/C3 (Tura et al., 2014), and high-molecular-weight melanoma-associated antigen (MHW-MAA).