In this study, we first screened out TNBC specific lncRNA Lnc-BTG3-7:1, which sustained tumor progress, and this TNBC specific lncRNA and its target C21ORF91 gene were involved in Wnt/β-catenin and MAPK pathways, which were associated with cancer cell progress (Liu et al., 2019). Here, C21orf91 is linked to cancer.