To determine whether mRNA species known to associate with fragile X mental retardation protein (FMRP) (Pasciuto and Bagni, 2014b) are differentially expressed as proteins in FXTAS cortexes, the list of known FMRP-associated mRNAs was compared to the FXTAS proteome. This evidence concerns the gene FMR1 and fragile X-associated tremor/ataxia syndrome.