SARS-CoV-2 NSP7 and ORF8 can inhibit several phagocytoses, promoting receptors such as scavenger receptors and integrins (Figure 7A); SARS-CoV-2 NSP6 and M protein might block v-ATPase, thus preventing the lowering of pH inside phagosome and preventing its maturation (Figure 7A); SARS-CoV-2 NSP7 prevents the phagosome-endosome/lysosome fusion by targeting Rab5 GTPase, which might result in viral pneumonia (Jakab et al., 1980) (Figure 7A). The gene discussed is RAB5A; the disease is viral pneumonia.