However, the broad associations of Tbx20 with multiple biological events in multiple cardiogenic cell lineages during cardiac development make it difficult to map out all Tbx20-mediated upstream and downstream genetic networks intercellularly and/or intracellularly, especially the correlation of its genetic mutations found in complex CHD and cardiomyopathy patients with unique disease outcomes. This evidence concerns the gene TBX20 and cardiomyopathy.