Wnt3, Wnt6 and Wnt11 are likewise upregulated in CRC in correlation with poor survival rate, and when downregulated proliferation and migration are suppressed and apoptosis is induced (Zheng and Yu, 2018; Gorrono-Etxebarria et al., 2019; Nie et al., 2019; Peng et al., 2019) (Figure 3). This evidence concerns the gene WNT6 and colorectal carcinoma.