NTRK1 and small cell lung carcinoma: The constitutively active mutant form of the non-receptor tyrosine kinase Src has likewise been reported to accumulate in the lipid rafts of small cell lung cancer (SCLC) cells and stimulate oncogenic phosphoinositide 3-kinase (PI3K) signaling by facilitating the interaction of particular PI3K isoforms with Src kinases (Arcaro et al., 2007).