DSCAML1 and neurodevelopmental disorder: On the other hand, DSCAML1 has been mapped to the 11q23 region, implicated in the pathophysiology of neurodevelopmental disorders including Jacobsen, Gilles de la Tourette, and distal trisomy 11q syndromes which points to DSCAML1 as a potential causative gene, although a clear causation has not been proven (Agarwala et al., 2001; Pauls, 2003; Mattina et al., 2009; Chen et al., 2014; Choi et al., 2015).