The BAMBI (Vanhara and Souček, 2013), LCN2 (Wang and Zeng, 2014), F13A1 (Vairaktaris et al., 2007), CDKN2A (Exner et al., 2015), SLIT2 (Chen et al., 2013), and CLU (Shapiro et al., 2015) were reported to individually play a role in cancer development and progression. The gene discussed is CLU; the disease is cancer.