Seven HCGs those were targeted by miR-30-5p family were FOSL2, GBP2, IL2RA, SOCS1, SOCS3, TMEM86A, TNIP1. These factors were reported to be involved in various bacterial infections and other diseases (Cha et al., 2013; Degrandi et al., 2013; Goudy et al., 2013; Muth et al., 2017; Ling et al., 2018; Shamilov and Aneskievich, 2018; De Oyarzabal et al., 2019; Place et al., 2020). This evidence concerns the gene TMEM86A and bacterial infectious disease.