Interferons (IFNs) and pro-inflammatory cytokines like IL6 were additionally reported to play crucial roles during Listeria infection that might be connected to SOCS proteins in the Listeria infected system (Stoiber et al., 2001; Hoge et al., 2013; Pitts et al., 2016; Hop et al., 2019). This evidence concerns the gene CISH and listeriosis.