Methylated C9orf50 was positive in 25.7% (26/101) of SP, 50.0% (10/20) of AA, 60.0% (3/5) of stage 0 CRC, 90.6% (29/32) of stage I CRC, 87.9% (51/58) of stage II CRC, 84.7% (50/59) of stage III CRC, 85.7% (18/21) of stage IV CRC, and 82.6% (19/23) of CRC of unknown stage. Here, C9orf50 is linked to colorectal carcinoma.