When methylated KCNQ5 and methylated C9orf50 were combined for CRC detection, the sensitivity and the specificity were 88.4% (95% CI: 82.9–92.3%) and 89.4% (95% CI: 82.8–93.7%), respectively (Figure 3A). The gene discussed is KCNQ5; the disease is colorectal carcinoma.