LTF and melanoma: Compared with the normal melanocytes, IGHV1-18, CXCL11 and HLA-DQB1 were highly expressed in melanoma cell line A375, A815 and SK-MEL-28, and LTF was downregulated in melanoma cell line A375, A815 and SK-MEL-28 (Figure 9), and both had statistical significance (P < 0.05).