DIRAS1, FBXL16, TP53I11, TFF2, and ZNF467 were upregulated in both metastatic tumors and GHSROS-overexpressing PC3 and LNCaP cells, while AASS, CHRDL1, CNTN1, IFI16, and MUM1L1 were downregulated. This evidence concerns the gene DIRAS1 and metastatic neoplasm.