The statistically significant increase in ICAM-1 serum levels among patients with COVID-19 compared with their non-COVID-19 counterparts supports the inclusion of this metric as a preliminary screening method for SARS-CoV-2 infection particularly for asymptomatic patients prior to surgery or other medical procedures to enable healthcare workers to take the proper precautions when providing care for these patients. Here, ICAM1 is linked to COVID-19.