Cav1.2 has been reported in association with four complex diseases: ASD (Jiang et al., 2013), intellectual disability (Hu et al., 2019), schizophrenia (Roussos et al., 2014), and epileptic encephalopathies (Bozarth et al., 2018). Here, CACNA1C is linked to Epileptic encephalopathy.