In addition, Cav1.2 mutations cause a range of common disorders including cardiomyopathy (D’Argenio et al., 2014), atrial or ventricular fibrillation (Maltese et al., 2019), bradycardia (Zhu et al., 2018), and cerebellar ataxia (Chen et al., 2019), which are both autosomal dominant and recessively inherited. Here, CACNA1C is linked to aceruloplasminemia.