Additionally, human cell lines with the p.Arg729Trp variant displayed inefficient splicing of a number of introns whose decreased splicing is associated with PRPF-linked RP in cell lines from various RP patients with PRPF3, PRPF31, and PRPF8 variants (Tanackovic et al., 2011a,b). The gene discussed is PRPF31; the disease is retinitis pigmentosa 1.