ENO1 and cancer: As mentioned above, ENO1 depletion attenuates glycolysis, cell proliferation, EMT, migration, and invasion, and metastasis in several cancer types (Fu et al., 2015; Capello et al., 2016; Principe et al., 2017; Zhan et al., 2017; Ji et al., 2019; Sun et al., 2019).