ENO1 and neoplasm: Alpha-enolase is overexpressed in multiple human cancer types, contributing to increased glycolysis and tumor growth (Altenberg and Greulich, 2004; Chang et al., 2006; He et al., 2007; Tsai et al., 2010; Capello et al., 2011; Song et al., 2014; Fu et al., 2015; Sun et al., 2017, 2019; Zhan et al., 2017; Yin et al., 2018; Zhang et al., 2018, 2020; Cheng et al., 2019; Ji et al., 2019; Qiao et al., 2019; Xu et al., 2019; Chen et al., 2020).