CHD2 and epilepsy: Another group of genes, CHD2, SCN10A, and TBC1D8, was associated with HGF and PTEN; these two genes are related to synaptic plasticity, neuronal cell survival, and CNS development, as well as related to epilepsy (Bae et al., 2010; Tonges et al., 2011; Sperow et al., 2012; Knafo and Esteban, 2017; Godale and Danzer, 2018).