METTL3 and acute myeloid leukemia: For example, the m6A methyltransferases METTL3/14 and WTAP could act as oncogenic factors by promoting the translation of several oncogenes including c-MYC, BCL2, PTEN, and mTOR in acute myeloid leukemia (Bansal et al., 2014; Vu et al., 2017; Sorci et al., 2018; Weng et al., 2018).