With regards to sIL-2Rα and IL-8 which was revealed to be associated with duration of illness of COVID-19 in this study, levels of sIL-2Rα were positively correlated with age (r=0.52, Padjusted<0.001), TNF-α (r=0.68, Padjusted<0.001), IL-6 (r=0.47, Padjusted<0.01), IL-10 (r=0.36, Padjusted<0.05), WBC (r=0.44, Padjusted<0.01), neutrophils (r=0.45, Padjusted<0.01), and NLR (r=0.41, Padjusted<0.01), while no significant correlation was revealed between IL-8 and any parameters. The gene discussed is IL6; the disease is COVID-19.