The allelic distribution of TIM3 rs10515746 and ICOS rs6726035 was also related to ITP susceptibility after combined analysis (OR = 3.218, 95% CI = 1.043–9.924, p = 0.042 and OR = 1.276, 95% CI = 1.015–1.605, p = 0.037, respectively; Table 4). The gene discussed is ICOS; the disease is autoimmune thrombocytopenic purpura.