In clinical studies of DC vaccines in ovarian cancer patients, alterations of immune cells in the peripheral blood sample after DCs infusion have been demonstrated, including the activation of specific antigen-induced IFN-γ secreting CD8+ T cells (58, 59, 62), an increased count of CD4+T cells (16) and Th1 polarization (58, 86). Here, CD4 is linked to ovarian carcinoma.