HLA-DRB1 and pemphigus vulgaris: Different alleles, HLA-DRB1*04:04,14:02 and 14:06 all share a sequence in the hypervariable region in residues 67 to 74 (LLEQRRAA) and these alleles were reported to be linked to fogo selvagem, an endemic form of pemphigus vulgaris (24).