IFNG and synovial sarcoma: IFN-γ is closely connected to the death of parotid epithelial cells in the salivary glands (70, 71) IFN-γ significantly recruits the chemokines CXCL9 and CXCL10 on the surface of submandibular epithelial cells, then immune cells home to lesions, and exacerbate the progression of SS (35, 86) (Figure 1).