Although we did not distinguish between the possibilities that T cells with reduced CD5 prior to infiltration into tumors were preferentially recruited into tumors, or that T cells with elevated CD5 infiltrated tumors but had their CD5 levels reduced within the tumor microenvironment, CD5 levels in T cells have been reported to be induced in correlation with the intensity of antigen recognition by TCR (24). The gene discussed is CD5; the disease is neoplasm.