The 13 pathways, including melanogenesis, pertussis, spliceosome, oxytocin signaling pathway, platelet activation, tyrosine metabolism, focal adhesion, fluid shear stress, and atherosclerosis, human papillomavirus infection, tight junction, PI3K-Akt signaling pathway, alcoholism, and complement and coagulation cascades, were significantly different (P < 0.05) in response to V. parahaemolyticus infection if judged by the P-value on the basis of Fisher’s exact test (Figure 5C). Here, AKT1 is linked to alcohol dependence.