To further understand the effects of various medications on the expression of PPAR-γ, we analyzed the mRNA expression level of PPAR-γ in the CD14+ monocytes from SLE patients treated with different drugs, including 6 patients treated with glucocorticoids, 9 patients treated with glucocorticoids combined with hydroxychloroquine, and 9 untreated patients; CD14+ monocytes from 21 healthy controls were also included in this experiment. This evidence concerns the gene CD14 and systemic lupus erythematosus.