TNFRSF13B and systemic lupus erythematosus: Moreover, macrophages with transmembrane activator and calcium-modulator and cyclophilin interactor (TACI)–deficient present an M2-skewed phenotype and improved the survival of MRL-Fas/Lpr mice, and the transfer of macrophages from TACI−/− Lpr-mice ameliorated SLE-like symptoms in age-matched, sick, wild-type mice (29).