The miRNAs significantly repressed in the 3rd trimester were used to search for possible interactions with the TERT, PURB, CRHR2, JUNB, IGF2R genes which are up-regulated during MS pregnancy; this showed that the mRNAs PURB and IGF2R were possible targets for six and four of the miRNAs, respectively, with the lowest confidence scores seen for PURB and miR-20a-5p (Table 6A). The gene discussed is CRHR2; the disease is myeloid sarcoma.