TLR9 and metabolic dysfunction-associated steatohepatitis: In a collaboration between Akita University and UCSD with Bernd Schnabl, Jerrold Olefsky, David Brenner, and Ekihiro Seki, Miura et al. first published on NASH in TLR9 knockouts (KOs) motivated by their interest in the TLR-MyD88 pathway in 2010 (131).