FGFR1 has been reported in promoting the proliferation of HSCs (de Haan et al., 2003; Magnusson et al., 2005; Zhao et al., 2012) and FGFR1 or its fusion protein drives AML development (Karajannis et al., 2006; Lee et al., 2013; Wang et al., 2016). This evidence concerns the gene FGFR1 and acute myeloid leukemia.