FGFR3 and chronic myelogenous leukemia, BCR-ABL1 positive: FGFR3, an important member of the FGFR family, is highly expressed in HSCs (Dvorak and Hampl, 2005), and increased in LSCs (CD34+BCR-ABL+) from chronic myeloid leukemia (CML) (Dvorak et al., 2003).