In this study, we screened eight P2 receptors which were commonly reported in cancer—the vast majority of these studies relate to P2X7, P2Y2 and P2Y12 receptors (Adinolfi et al., 2012; Li et al., 2013; Chadet et al., 2014; Jin et al., 2014). The gene discussed is P2RY2; the disease is cancer.