GNAQ and Anxiety: Together, these ground-breaking studies suggest that the regulation of learning and memory processes and anxiety-related behaviors, are directly linked to M1 mAChR phosphorylation and subsequent downstream signaling pathways, such as β-arrestin recruitment, whereas, adverse effects such as salivation, seizures, and hyperactivity are linked to Gαq, IP3 and calcium signaling pathways (Bradley et al., 2020).