Chau and coworkers determined matrix metalloproteinase- (MMP-) 2 and MMP-9 levels in the plasma collected from AMD suffering patients, highlighting that plasmatic MMP-9 levels were significantly higher in age-related maculopathy and choroidal neovascularization (CNV) groups, as compared to control groups (Chau et al., 2008). This evidence concerns the gene MMP9 and age-related macular degeneration.