MAPK1 and pneumonia: Wu et al. (2020b) showed that the QFPDD compound-pneumonia target network contained 292 compounds and 214 corresponding potential targets and the top five pivotal targets were AKT serine/threonine kinase 1 (AKT1), interleukin-6 (IL-6), mitogen-activated protein kinase 8 (MAPK8), mitogen-activated protein kinase 1 (MAPK1), and jun proto-oncogene (JUN).