SCN1A and Dravet syndrome: The most common murine models for DS are based on total or partial deletions of Scn1a gene or expression of specific human point mutations found in this gene, always under different promoters and allowing total or conditional (using Cre-loxP strategies) gene manipulations (Oakley et al., 2001; Yu et al., 2006; Ogiwara et al., 2007; Tang et al., 2009; Martin et al., 2010; Cheah et al., 2012; Dutton et al., 2013; Miller et al., 2014; Rubinstein et al., 2015; Tsai et al., 2015; Griffin et al., 2018).