PBMCs from those exposed to TB also showed some features consistent with innate immune training, e.g. elevation of innate immune cytokines IL-1β, TNFα or IL-6 in response to BCG stimulation and higher CXCL10 production in response to heterologous stimuli, although monocyte TNFα was not associated with improved mycobacterial growth inhibition. This evidence concerns the gene CXCL10 and tuberculosis.