A study by Joosten et al. found that enhanced secretion of CXCL9 and CXCL10 by non-classical monocytes was associated with greater mycobacterial growth inhibition in individuals who were exposed to TB but not infected, compared to TB patients or healthy controls, although central memory T-cell responses and B-cell frequencies were also associated with control of mycobacterial growth [34]. This evidence concerns the gene CXCL10 and tuberculosis.