Furthermore, MYBPHL was previously shown to induce a form of DCM in human and mouse.26MYBPHL is a predicted target of 3 of the upregulated miRNAs, and its expression is reduced both after inhibition of cTTN1 in hiPSC-CMs and in RBM20 mutation carriers (Excel File VI and Figure VIIIc–VIIIe in the Data Supplement). This evidence concerns the gene RBM20 and familial dilated cardiomyopathy.