HIF1A and idiopathic pulmonary fibrosis: As demonstrated in our study, BLM induces a diffuse and massive expression of HIF1α in mice lungs which is rather different from HIF1α signal in IPF lung in which HIF1α expression has been shown to be more restricted to hyperplastic alveolar epithelial cells and not (myo)fibroblasts [10, 15, 31].