PKHD1 and polycystic kidney disease: Additionally, in a recent study by Li et al on polycystic kidney disease (PKD), HNF1B was shown to have been regulated by p53S, a mutant version of the tumour suppressor p53. 82RNA‐seq analysis to understand PKD in p53 mutant mice, revealed the suppression of PKD1, PKD2, Pkhd1 (polyductin) and HNF1B expression.